HEAD & SHOULDERS CITRUS FRESH 2-IN-1

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Head & Shoulders Citrus Fresh 2-in-1 is a pyrithione zinc 1% anti-dandruff shampoo and conditioner in one bottle, formulated to control flaking and itching associated with dandruff while cleansing and conditioning hair . Infused with yuzu, mint, lemon, and eucalyptus essence, the citrus fresh scent purifies greasy scalp and leaves hair smelling clean and refreshed . The Microbiome Balance formula targets the root cause of dandruff by maintaining a healthy scalp pH and microbiome, releasing 2x more protective ingredients into pores to prevent stubborn dandruff from returning with regular use . Clinically proven to provide up to 100% visible flake control, the formula contains 25% more conditioning agents than regular Head & Shoulders Shampoo for deeply moisturised, soft, radiant hair . Paraben-free, pH-balanced, dermatologically tested, and suitable for daily use on all hair types, including colour-treated and greasy hair . For external use only. Avoid contact with eyes. If condition worsens or does not improve, consult a doctor. Keep out of reach of children.
Description

HEAD & SHOULDERS CITRUS FRESH 2-IN-1 

PRIMARY USES

1. Dandruff Protection with Refreshing Citrus Scent for Greasy Scalp and Hair
Primary Use: Provides 1% pyrithione zinc anti-dandruff efficacy combined with conditioning agents in a convenient 2-in-1 formula, controlling flaking and itching associated with dandruff while cleansing and conditioning hair, specifically formulated to purify greasy scalp and hair .
How it helps: For the dermatologist and primary care physician, patients with dandruff often experience concurrent greasiness and oiliness of the scalp, which exacerbates flaking and discomfort. The Citrus Fresh 2-in-1 formula targets the root cause of dandruff (Malassezia yeast) with pyrithione zinc 1%, while the fresh, zesty blend of lemon, mint, yuzu, and eucalyptus essence invigorates the scalp and leaves hair smelling clean and refreshed . The formula works deep at the source against three scalp issues: dandruff, oil, and itch related to dandruff . For the patient, this means effective dandruff control that leaves both scalp and hair feeling airy, clean, and refreshed.
2. Clinically Proven Flake Protection with Microbiome Balance Technology
Primary Use: Clinically proven to provide up to 100% visible flake control with regular use, the Microbiome Balance formula targets the root cause of dandruff by maintaining a healthy scalp pH and microbiome balance, releasing protective ingredients that penetrate deep into pores to prevent stubborn dandruff from returning .
How it helps: For the healthcare professional, scalp microbiome imbalance is central to dandruff pathogenesis and recurrence. The Citrus Fresh 2-in-1 formulation works both against visible and invisible dandruff by releasing 2x more protective ingredients that go into the pores to finally prevent stubborn dandruff from coming back . The pH-balanced formula provides gentle care for both scalp and hair while maintaining the skin’s natural protective barrier. For the patient, this means progressive improvement with each wash—scalp hydration improves, irritation reduces, and dandruff recurrence is prevented.
3. 2-in-1 Format with 25% More Conditioning Agents for Moisturised Hair
Primary Use: Combines shampoo and conditioner in one bottle with 25% more conditioning agents vs. regular Head & Shoulders Shampoo, deeply moisturising and nourishing hair while controlling dandruff, leaving hair clean, soft, and radiant .
How it helps: For the busy patient and dermatologist, streamlining hair care routines improves adherence to anti-dandruff regimens while ensuring hair remains healthy and manageable. The 2-in-1 variant delivers the same pyrithione zinc 1% active ingredient while also conditioning the hair, reducing the number of steps in the patient’s shower routine . The formula deeply moisturises and nourishes hair, leaving it clean, soft, and radiant (best results when used daily) . For the patient, this means a single, convenient product that treats dandruff effectively while leaving hair feeling soft, moisturised, and beautifully scented.
4. Paraben-Free, pH-Balanced Formula Suitable for All Hair Types
Primary Use: Paraben-free, pH-balanced, dermatologically tested formula that is safe for daily use on all hair types, including colour-treated, curly, and greasy hair, suitable for both men and women .
How it helps: For the general practitioner and patient, selecting an anti-dandruff product that won’t damage hair quality or cause irritation is essential for long-term adherence. The Citrus Fresh 2-in-1 formula is specifically designed to be gentle on both scalp and hair, with a paraben-free, pH-balanced composition that maintains the skin’s natural protective barrier . It is clinically proven, dermatologically tested, and an ideal everyday shampoo for men and women for any hair and scalp type . For the patient, this means a single, reliable product that treats their dandruff without forcing trade-offs in hair appearance or style.

SECONDARY USES

1. Management of seborrheic dermatitis of the scalp: For patients with mild to moderate seborrheic dermatitis, the 1% pyrithione zinc formulation helps control the inflammatory scaling and itching characteristic of this chronic condition, with the 2-in-1 format providing added convenience for daily use.
2. Purifying treatment for greasy scalp and hair: For patients with naturally oily scalps who experience rapid greasiness between washes, the Citrus Fresh formula purifies greasy scalp and hair, leaving them feeling clean and refreshed for longer periods .
3. Prevention of dandruff recurrence in maintenance phase: For patients who have successfully cleared active dandruff, using Citrus Fresh 2-in-1 regularly helps maintain scalp health and prevent relapse, with the conditioning formula ensuring hair remains manageable and fresh.
4. Family dandruff management across different hair types: The gentle, pH-balanced formula is suitable for men, women, and teenagers with all hair types, providing consistent dandruff control across different household members with a single product .
5. Daily use for patients seeking a refreshing, invigorating scalp sensation: For patients who prefer an energising, citrus-scented shower experience, the yuzu, mint, lemon, and eucalyptus-infused formula provides an invigorating scalp sensation that awakens the senses and leaves hair smelling fresh .
KEY PRODUCT FEATURES

1. BASIC IDENTIFICATION ATTRIBUTES

  • Device Type: Over-the-counter (OTC) topical anti-dandruff shampoo and conditioner; non-prescription medication
  • Brand: Head & Shoulders 
  • Designation: Citrus Fresh 2-in-1, Citrus Fresh 2in1 Shampoo + Conditioner
  • Active Ingredient: Pyrithione zinc 1% w/v 
  • Therapeutic Classification: Anti-dandruff / Antifungal (OTC monograph part 358H)
  • Product Type: 2-in-1 (shampoo + conditioner combined)
  • Available Sizes: 270mL, 330mL, 400mL, 625mL, 13.5 fl oz (400mL), 1,620mL (6 x 270mL multi-pack) 
  • Fragrance Notes: Citrus fresh with yuzu and mint essence; lemon fruit extract; eucalyptol; camphor; menthol 
  • Paraben-Free: Yes 

2. TECHNICAL & PERFORMANCE PROPERTIES

  • Active Ingredient Concentration: 1 gram pyrithione zinc per 100 mL
  • Mechanism of Action: Pyrithione zinc exhibits antifungal activity against Malassezia species, inhibiting yeast growth and reducing inflammatory response, thereby controlling flaking, scaling, and pruritus associated with dandruff and seborrheic dermatitis
  • Clinical Efficacy: Up to 100% visible flake protection with regular use; clinically proven 
  • Conditioning Enhancement: Contains 25% more conditioning agents vs. regular Head & Shoulders Shampoo 
  • Protection Formula: 3X Protection Formula works against three scalp issues: dandruff, oil, and itch related to dandruff 
  • Microbiome Technology: Microbiome Balance formula targets root cause by maintaining healthy pH and scalp microbiome balance; releases 2x more protective ingredients vs. regular formula 
  • Dermatological Testing: Dermatologically tested; pH-balanced; clinically proven 
  • Consistency: Liquid (2-in-1 shampoo + conditioner)
  • Appearance: White liquid; no artificial colours may be indicated in some variants 
  • Inactive Ingredients: Water, sodium lauryl sulfate, sodium laureth sulfate, glycol distearate, zinc carbonate, sodium chloride, sodium xylenesulfonate, fragrance, cocamidopropyl betaine, dimethicone, menthol, sodium benzoate, guar hydroxypropyltrimonium chloride, magnesium carbonate hydroxide, citrus limon (lemon) fruit extract, methylchloroisothiazolinone, methylisothiazolinone, eucalyptol, camphor, yellow 5, blue 1 
  • Preservatives: Methylchloroisothiazolinone, methylisothiazolinone, sodium benzoate
  • Fragrance Components: Yuzu, mint, lemon fruit extract, eucalyptol, camphor, menthol 
  • Certifications: No. 1 dermatologist recommended anti-dandruff shampoo brand 
  • Shelf Life: Not specified; typical for OTC shampoo products when stored properly
  • Allergen Information: Contains fragrance; may contain known allergens as fragrance components

3. PHYSICAL & OPERATIONAL PROPERTIES

  • Physical Form: Viscous liquid
  • Route of Administration: Topical (scalp and hair)
  • Preparation: Shake bottle before use 
  • Application Instructions: Wet hair thoroughly. Massage shampoo onto scalp, working into a rich lather. Rinse thoroughly. Repeat if desired 
  • Frequency of Use: For best results, use at least twice weekly. For maximum dandruff control, use every time you shampoo 
  • Treatment Duration: Use regularly as directed; improvement typically visible within 2 weeks of consistent use; continued use prevents recurrence
  • Storage Conditions: Store in a cool, dry place. Keep bottle tightly closed when not in use. Avoid extreme temperatures
  • Portion Size: Approximately one to two tablespoons per wash (depends on hair length and thickness)

4. SAFETY & COMPLIANCE ATTRIBUTES

  • OTC Monograph Status: Approved under FDA OTC Monograph Final Part 358H for anti-dandruff use
  • Indications: Helps prevent recurrence of flaking and itching associated with dandruff 
  • External Use Only: For topical use on scalp and hair only. Not for ingestion
  • Eye Contact Warning: Avoid contact with eyes. If contact occurs, rinse eyes thoroughly with water 
  • When to Stop Use: Discontinue if condition worsens or does not improve after regular use as directed. Consult a doctor
  • Paediatric Safety: Keep this and all drugs out of reach of children
  • Ingestion Warning: If swallowed, get medical help or contact a Poison Control Center right away
  • Quality Assurance: Manufactured by The Procter & Gamble Manufacturing Company 
  • Country of Origin: Made in USA of US and/or imported ingredients; also manufactured in France 
  • Satisfaction Guarantee: Satisfaction Guarantee available – return product with proof of purchase for refund 
SAFETY HANDLING PRECAUTIONS

1. SAFETY PRECAUTIONS

  • For external use only: This product is formulated for topical application to scalp and hair. Do not ingest. If swallowed, contact a Poison Control Center immediately.
  • Avoid eye contact: Pyrithione zinc and the citrus fragrance components can cause eye irritation. If shampoo enters eyes, rinse immediately and thoroughly with water. If irritation persists, seek medical advice .
  • Discontinue if irritation develops or condition worsens: While generally well-tolerated, some individuals may experience scalp irritation, dryness, or allergic contact dermatitis. Discontinue use if condition worsens or does not improve after regular use as directed.
  • Keep out of reach of children: Product contains active pharmaceutical ingredient. Store in a location where young children cannot access it to prevent accidental ingestion or misuse.
  • Appropriate use duration: For dandruff management, regular use is required for maintenance. Improvement typically occurs after 2 weeks of regular use.
  • Do not use on broken or irritated scalp: Avoid applying to areas of the scalp that are actively bleeding, oozing, or showing signs of infection. Seek medical advice for severe scalp conditions.
  • Patch test for sensitive individuals: For patients with known sensitive skin or history of contact dermatitis, consider patch testing on a small area of skin before full scalp application.
  • Not a treatment for systemic fungal infections: This product is intended for topical management of dandruff and seborrheic dermatitis of the scalp only.
  • Pregnancy and lactation: Pyrithione zinc 1% shampoo is generally considered safe for use during pregnancy and breastfeeding when used as directed. However, patients should consult their healthcare provider if concerned.
  • Proper disposal: Dispose of empty bottle in household waste. Do not recycle unless local facilities accept shampoo bottles.

2. FIRST AID MEASURES

  • Eye contact: If shampoo enters eyes, rinse immediately with plenty of lukewarm water for at least 15 minutes. Hold eyelids open during rinsing. If irritation, redness, or pain persists after rinsing, seek medical attention.
  • Ingestion: If swallowed, do not induce vomiting. Rinse mouth with water. Contact a Poison Control Center immediately or seek emergency medical attention. Provide product container or label to medical personnel.
  • Skin irritation (mild): Discontinue product use. Rinse affected area thoroughly with lukewarm water. Apply a gentle, fragrance-free moisturiser if dryness develops. If irritation persists beyond 48 hours, consult a healthcare professional.
  • Allergic contact dermatitis (rash, itching, redness): Discontinue use immediately. Wash scalp thoroughly with water. Apply cool compresses if itching is severe. Consult a dermatologist if symptoms are widespread or persistent.
  • Accidental ingestion by child: Call Poison Control Center immediately (1-800-222-1222 in US) or seek emergency medical care. Do not induce vomiting unless directed by medical professional.

3. FIRE FIGHTING MEASURES

  • Flammability: Shampoo is water-based and not considered flammable. However, plastic packaging may burn if exposed to open flame.
  • Extinguishing Media: Use water spray, foam, dry chemical powder, or carbon dioxide (COâ‚‚). No special restrictions apply.
  • Fire Response: For small fires involving packaging, use appropriate extinguisher. For large fires, evacuate area. Firefighters should wear self-contained breathing apparatus (SCBA) and full protective gear for fires involving burning plastics.
  • Hazardous decomposition products: Burning plastic packaging may release irritating fumes including carbon monoxide and acrid smoke.